Post-market drug surveillance projects developing slowly

Post-market drug surveillance projects developing slowly.

Pharmacovigilance and post-black market surveillance.

Pharmacovigilance can be defined as a set of practices aiming at the detection, understanding and assessment of risks related to the use of drugs in a population, and the prevention of consequential adverse effects. In a narrower sense, the term refers exclusively to postmarket surveillance. This paper briefly outlines how pharmacovigilance has come to play a central role in the regulation of n...

Post‐market drug surveillance sans trial costs: Discovery of adverse drug reactions via large‐scale analysis of Web search queries

Background: Postmarket drug safety surveillance largely depends on spontaneous reports by patients and healthcare providers, hence less common adverse drug reactions—especially those caused by long‐ term exposure, multidrug treatments, or specific to special populations—often elude discovery. Objective: Here we propose an ultra‐low‐cost fully automated method for continuous monitoring of advers...

Japanese Physicians’ Views on Drug Post-Marketing Surveillance

BACKGROUND Registration trials leading to the approval of drugs are paramount in drug development. After approval, continuous efforts are necessary to ensure proper use of the approved drugs. In Japan, post-marketing surveillance (PMS) by drug companies is conducted in accordance with good post-marketing study practice (GPSP). Although the global standard for pharmacovigilance is incorporated i...

Developing Intelligent Surveillance System

This paper describes a real time feature extraction for realtime surveillance system. We use incremental KPCA method in order to represent images in a low-dimensional subspace for realtime surveillance. In the traditional approach to calculate these eigenspace models, known as batch PCA method, model must capture all the images needed to build the internal representation. Updating of the existi...